Endocrine Abstracts

A 12-year-old girl was referred to the endocrinology clinic for investigation of short stature. She had signs of early puberty yet had precocious menstruation associated with menorrhagia. She gave a recent history of recurrent epistaxis. There was no family history of a bleeding disorder. She reported cold intolerance, dry skin and a tendency for hair to fall.On examination she was pale with no evidence of purpura or significant bruising. There was no en...

Introduction: Children with chronic renal failure may grow poorly and have altered bone metabolism and body composition. Post-renal transplant (Tx), improvement in these parameters may be hindered due to glucocorticoid exposure.Aims & methods: To study changes in these parameters after Tx, anthropometry, bone mineral content (BMC) at total body (TB) and lumber spine (LS), lean mass (LM) and fat mass (FM) were analysed by DXA in 15 children (median ag...

Background: Musculoskeletal symptoms are common but unrecognized symptoms of thyroid dysfunction. We present a case report of an elderly man presenting with acute paraparesis as the first manifestation of thyrotoxicosis.Case report: A 73-year man presented with 1-week history of weakness in both legs and inability to mobilize or stand. Neurological examination revealed severe proximal muscle weakness (grade 0/5 power) of both lower limbs with reduced ten...